University of Southern California

Crump Lab

USC Stem Cell

Selected Publications


  • Askary A, Mork L, Paul S, He X, Izuhara AK, Gopalakrishnan S, Ichida JK, McMahon AP, Dabizljevic S, Dale R, Mariani FV, Crump JG. Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State. Developmental Cell. 2015 Nov 9;35(3):358–65. doi: 10.1016/j.devcel.2015.10.004. PMID: 26555055. [PubMed] [PDF]
  • Choe CP, Crump JG. Eph-Pak2a signaling regulates branching of the pharyngeal endoderm by inhibiting late-stage epithelial dynamics. Development. 2015 Mar 15;142(6):1089–94. doi: 10.1242/dev.115774. PMID: 25725065. [PubMed] [PDF]


  • Choe CP, Crump JG. Tbx1 controls the morphogenesis of pharyngeal pouch epithelia through mesodermal Wnt11r and Fgf8a. Development. 2014 Sep;141(18):3583–93. doi: 10.1242/dev.111740. PMID: 25142463. [PubMed] [PDF]


  • Choe CP, Collazo A, Trinh le A, Pan, L, Moens CB, Crump, JG. Wnt-dependent epithelial transitions drive pharyngeal pouch formation. Developmental Cell. 2013 Feb 11;24(3), 296–309. doi: 10.1016/j.devcel.2012.12.003. PMID: 23375584. [PubMed] [PDF]


  • Cox S, Kim H, An W, Crump JG. An essential role of variant histone H3.3 in ectomesenchyme potential of the cranial neural crest. PLoS Genetics. 2012 Sep;8(9):e1002938. doi: 10.1371/journal.pgen.1002938. PMID: 23028350. [PubMed] [PDF]
  • Das A, Crump JG. Bmps and Id2a act upstream of Twist1 to restrict ectomesenchyme potential of the cranial neural crest. PLoS Genetics. 2012;8(5):e1002710. doi: 10.1371/journal.pgen.1002710. PMID: 22589745. [PubMed] [PDF]
  • Balczerski B, Matsutani M, Castillo P, Osborne N, Stainier D, Crump JG. Analysis of Sphingosine-1-phosphate signaling mutants reveals endodermal requirements for the growth but not dorsoventral patterning of jaw skeletal precursors. Developmental Biology. 2012 Feb 15;362(2):230–41. doi: 10.1016/j.ydbio.2011.12.010. PMID: 22185793. [PubMed] [PDF]


  • Zuniga E, Rippen M, Alexander C, Schilling TF, Crump JG. Gremlin2 regulates distinct roles of Bmp and endothelin1 signaling in dorsoventral patterning of the facial skeleton. Development. 2011 Dec;138(23):5147–56. doi: 10.1242/dev.067785. PMID: 22031546. [PubMed] [PDF]
  • Alexander C, Zuniga E, Blitz IL, Wada N, Le Pabic P, Javidan Y, Zhang T, Cho KW, Crump JG, Schilling TF. Combinatorial roles for Bmps and endothelin1 in patterning the dorsal-ventral axis of the craniofacial skeleton. Development. 2011 Dec;138(23):5135–46. doi: 10.1242/dev.067801. PMID: 22031543. [PubMed] [PDF]


  • Zuniga E, Stellabotte F, Crump JG. Jagged-Notch signaling ensures dorsal skeletal identity in the vertebrate face. Development. 2010 Jun;137(11):1843–52. doi: 10.1242/dev.049056. PMID: 20431122. [PubMed] [PDF]