Crump lab zebrafish header image

Pituitary puzzle gets a new piece, revising evolutionary history

A new USC-led study suggests a change to the developmental — and evolutionary — story of the pituitary gland. The pea-sized gland, nestled at the base of the brain, produces hormones that drive growth, aggression, sexual development and reproduction. For decades, the front lobe of the pituitary — where the hormones are made — was…Continue Reading Pituitary puzzle gets a new piece, revising evolutionary history

When it comes to arthritic bone spurs, stem cells hurt instead of heal

The same stem cells that heal broken bones can also generate arthritic bone spurs called osteophytes, according to a new study in the Annals of Rheumatic Diseases. “Although these stem and progenitor cells promote healthy bone repair in other contexts, they are inappropriately activated to cause a pathological bony protuberance in the context of arthritis,”…Continue Reading When it comes to arthritic bone spurs, stem cells hurt instead of heal